Scarmiglione is a demon who appears in Inferno of Dante's Divine Comedy. In the poem, he is part of a demonic troop called the Malebranche, who guard the fifth bolgia of Malebolge. The Malebolge is found in the eighth circle of Hell, Fraud, where corrupt politicians are immersed in burning pitch.
Depicted as a Hell spawn with poison claws, Skull Millione himself is not poisonous to touch, but his claw attacks are. Initially, he is found hovering in midair; when approached, he quickly positions above Soma and then lunges downward at great speed, attempting to poison him with his toxic claws.